Life expectancy numbers are skewed. If you take out violent deaths, the US looks much better. In many countries (like much of Europe), an infant does not count as a live birth until some days or weeks later, whereas in US it is live if it breathes at all on delivery. This makes US infant mortality look much worse.
As to costs, many of the US costs are because we are rich. Conditions that in other countries they simply don’t treat, we do treat. A big part of our expenses is end of life care which in poorer countries does not happen. Finally, optional costs (lasik, cosmetic surgery) and physical therapy/artificial legs etc do not happen in other countries but we can afford them.

“Roger Pilon correctly points out that the current drug pricing scheme effectively requires American payers to subsidize pharma R&D for the whole world. His solution to this is to move on and just accept this as a fact of life.”

There really is no other viable option.

” or else Congress will mandate prices equal to those of Canada or the EU”

If the US Congress goes there, it will result in a massive reduction of privately funded pharma R&D. We either simply either do without new & better drugs or governments will have to step in and directly conduct/fund pharmaceutical R&D. The latter option, if put on the US alone is likely to cost far more in the long run than following Roger Pilon’s advice.